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Study on the mechanism of supplementing qi and nourishing yin therapy against lung adenocarcinoma based on ALYREF mediated modification of PFKP m5C to regulate glucose metabolism reprogramming

Study on the mechanism of supplementing qi and nourishing yin therapy against lung adenocarcinoma based on ALYREF mediated modification of PFKP m5C to regulate glucose metabolism reprogramming

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103733
Enrollment
Unknown
Registered
2025-06-05
Start date
2025-06-15
Completion date
Unknown
Last updated
2025-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung adenocarcinoma

Interventions

Observation group :None

Sponsors

The First Affiliated Hospital of Hunan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 80 years old, regardless of gender; 2. It meets the relevant diagnostic criteria in the 2021 edition of the Guidelines for Clinical Diagnosis and Treatment of Lung Cancer of the Oncology Branch of the Chinese Medical Association, and is confirmed by electronic bronchoscopy biopsy, lung surgery biopsy and other relevant examinations; 3. Judge the degree of disease and comorbidities without interference from other diseases; 4. No targeted treatment such as chemotherapy or radiotherapy has been performed before operation; 5. Informed consent to this study.

Exclusion criteria

Exclusion criteria: 1. Incomplete or lost clinical data; 2. Accompanied by other tumors; 3. Severe infection or long-term use of hormones; 4. In pregnancy or breastfeeding.

Design outcomes

Primary

MeasureTime frame
ALYREF/PFKP expression;m^5C modification level;

Countries

China

Contacts

Public ContactZhaojun Xu

The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Xuzj1492@163.com+86 139 7511 2442

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026