Coronary heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a. Approved by the Ethics Committee of Shanxi Medical University and written informed consent from the patient (or authorized representative) b. Meets the standard for CABG surgery and can tolerate the surgery c. ASA grade II-III, age 50-75 years d. Body Mass Index (BMI) 18.5-28 kg/m^2
Exclusion criteria
Exclusion criteria: a. Previous history of heart disease surgery b. Severe dysfunction of major organs (such as liver or kidney failure) c. Long-term use of opioids and NSAIDs in the past d. Allergic to drugs used in the trial or have contraindications for drug use e. Mental illness or cognitive dysfunction and communication disorders f. Presence of malignant tumors in other tissues of the body g. Abnormal coagulation function before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to remove tracheal tube;NRS scores at different times after extubation;Total amount of tramadol used within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of sufentanil used during surgery;Time from removal of tracheal tube to first postoperative rescue analgesia;Patient's BCS comfort rating at different times; | — |
Countries
China
Contacts
Shanxi Province Cardiovascular Disease Hospital