Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Reference: Based on the 2021 Expert Consensus on Body Weight Management Procedures for Overweight/Obese Populations issued by the Health Management Branch of the Chinese Medical Association: Overweight: 24 kg/m^2 = 28 kg/m^2 Central obesity (adults): Waist circumference = 90 cm (male) or = 85 cm (female). Inclusion Criteria: Meeting the diagnostic criteria for overweight or obesity; Aged 16–65 years; No concurrent use of medications that may affect body weight; Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria:Secondary obesity caused by:Hypothalamic disorders;Endocrine diseases (e.g., hypercortisolism, hypothyroidism, insulinoma);Medication-induced weight gain;Pregnancy, lactation, or women planning pregnancy within 6 months;Severe primary diseases of major organs (heart, liver, kidney);Coexisting severe conditions:Coagulation disorders;Infectious diseases;Malignancies;Liver cirrhosis;Any weight-loss medication or treatment within 3 months prior to enrollment, or >5% body weight reduction during this period;Inability to comply with treatment and follow-up protocols
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight;waist circumference;body fat percentage; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood glucose;blood lipids;blood insulin ;uric Acid;gut microbiota; | — |
Countries
China
Contacts
Tai'an Central Hospital