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Research on the Molecular Mechanism of Sepsis-Induced Acute Lung Injury Based on Bioinformatics Analysis Data

Research on the Molecular Mechanism of Sepsis-Induced Acute Lung Injury Based on Bioinformatics Analysis Data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103566
Enrollment
Unknown
Registered
2025-05-30
Start date
2025-06-05
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lung injury

Interventions

Healthy control group:NA
Disease group:NA

Sponsors

First People's Hospital of Huzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for sepsis (Sepsis-3 criteria): when a confirmed or suspected infection patient shows an acute increase in the Sequential Organ Failure Assessment (SOFA) score of >=2 points. 2. Meets the diagnostic criteria for Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS) (Berlin criteria). 3. Ages 18-80, gender unrestricted. 4. The patient or their family members sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Merge with other lung diseases (such as lung cancer); 2. Immunodeficiency diseases or long-term use of immunosuppressants. 3. Malignant tumors or end-stage organ failure;

Design outcomes

Primary

MeasureTime frame
Relative expression level of genes;—

Secondary

MeasureTime frame
CRP;Inflammatory factors;—

Countries

China

Contacts

Public ContactLiu Tao

First People's Hospital of Huzhou

18267250026@139.com+86 572 2508930

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026