Cardiovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Clinically diagnosed as patient with HF; 2.Aged for 18-74 years old; 3.NYHA class ?-?;
Exclusion criteria
Exclusion criteria: 1. Smokers and alcoholics; 2. Those who took or injected VB6 3 months before admission; 3. Patients who are taking drugs that affect VB6 absorption, including anti-epileptic drugs, anti-tuberculosis drugs, contraceptives and estrogen drugs; 4. Those with VB6 allergy; 5. Those who are receiving cognitive training or participating in other interventional investigators; 6. Combined with neurological diseases, such as Alzheimer's disease, Parkinson's disease, etc.; 7. Combined with digestive system diseases, such as inflammatory bowel disease, ulcerative colitis, etc.; 8. Combined psychiatric diseases, such as depression, schizophrenia, etc.; 9. History of cancer; 10. Combined with autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, etc.; 11. Co-existing infectious diseases, such as AIDS, tuberculosis, etc.; 12. Those who are unable to cooperate with the completion of cognitive assessment such as hearing and hearing impairment; 13. Lactating or pregnant women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| VB6 level;Inflammation level;Tryptophan level; | — |
Countries
China
Contacts
Fujian Medical University Union Hospital