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A study of the effect of CACR on cognitive function in non-demented patients with post-stroke cognitive impairment

A study of the effect of CACR on cognitive function in non-demented patients with post-stroke cognitive impairment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103557
Enrollment
Unknown
Registered
2025-05-30
Start date
2023-03-02
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke cognitive impairment

Interventions

treatment group:Traditional Cognitive Training+Computer Assisted Cognitive Rehabilitation

Sponsors

Jiaxing Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1 Meet the diagnostic criteria of ischemic stroke in the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018, and confirmed by cranial CT or MR, with a disease duration of 3 to 6 months; 2 Meet the diagnostic criteria of PSCIND in the Expert Consensus on Management of Cognitive Impairment after Stroke 2017, and complete the rating of the Mini-Mental State Examination (MMSE) or Montreal cognitive assessment (MoCA); 3 Aged 45-75 years old, and education level of elementary school and above; 4Ability to cooperate in completing the assessment and rehabilitation training in the study; 5Signed informed consent.

Exclusion criteria

Exclusion criteria: 1Patients with serious complications or cardiopulmonary diseases and other conditions in an unstable state; 2 A history of cognitive impairment before stroke, and a questionnaire > 3.38 for those informed about cognitive decompensation in the elderly; 3 Presence of diseases affecting cognitive function, such as recurrent epileptic seizures, encephalitis, hydrocephalus, etc; 4 With post-stroke depression, Burns Depression Inventory Self-Rating Scale > 11 or Hamilton Depression Scale >= 17; 5 Presence of factors affecting rehabilitation training or assessment, e.g., severe psychiatric symptoms, aphasia, visual and hearing impairment, bone fracture, quadriplegia, etc; 6 Those who refuse to sign the informed consent or do not cooperate with the assessment and treatment.

Design outcomes

Primary

MeasureTime frame
Event-related potential P300;symbol digit modalities test;trail making test;auditory verbal learning test;Clock Test;Boston Naming Test;

Countries

China

Contacts

Public ContactJia Liu

Jiaxing Second Hospital

405535460@qq.com+86 182 5832 4207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026