Patients with clinically highly suspected or histopathology hepatocellular carcinoma
Conditions
Interventions
Gold Standard:The final diagnostic criteria were histopathology biopsy or surgical specimen, or a definite clinical diagnosis
Index test:SPECT imaging
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.the subject or his/her legal representative can sign and date the informed consent form; 2.commitment to follow the research procedures and cooperate in the implementation of the full-process research; 3.patients with high clinical suspicion or histopathology diagnosis of HCC and generally in good condition; 4.patients with a history of hepatocellular carcinoma who recur after treatment; 5.women in their reproductive years were using contraception for at least one month before screening and were committed to using contraception throughout the study period and for the prescribed period after the end of the study;
Exclusion criteria
Exclusion criteria: 1.inability to complete SPECTCT examination (including inability to lie down, claustrophobia, radiophobia, etc.); 2.acute systemic diseases and electrolyte disorders; 3.patients with known hypersensitivity to GPC3 imaging agents or synthetic excipients; 4.patients considered by the investigator to have poor adherence; 5.pregnant or lactating patients; 6.Have other factors not suitable to participate in this test;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiation dose to human body;Region of Interest,ROI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathological results of tumour tissue;Radioactivity in the blood and urine samples; | — |
Countries
China
Contacts
Public ContactXiaoli Lan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed