Bone defect filling during mandibular cyst removal surgery
Conditions
Interventions
Test group:Calcium-silicon bioceramic bone repair material filling repair
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age range of 18-70 years old (including upper and lower limits), gender is not limited; 2.The maximum diameter of the jawbone cyst is between 2cm-4cm, and the lingual bone wall is intact; 3.The number of affected teeth is 2-3; 4.Removal of jaw cyst combined with guided bone regeneration technology is required for bone defect repair; 5.Participants voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with cyst infection; 2.Patients with polycystic, multiple or recurrent jaw cysts; 3.Patients with maxillofacial space occupying lesions or malignant tumors in other parts of the body; 4.Patients with a history of acute periapical periodontitis, progressive periodontal disease, and refractory periodontitis; 5.Patients with bone metabolism disorders (such as osteoporosis, abnormal osteoarthritis, etc.), or those who have taken drugs or products that can significantly affect bone metabolism (such as steroids, bisphosphonates, etc).within the past 3 months before enrollment; 6.Patients with a history of head and neck radiotherapy; 7.Patients who are unable to undergo oral imaging examinations and those who may experience dental imaging artifacts that affect outcome evaluation; 8.Patients who have taken anticoagulant drugs or have abnormal coagulation function in the past 3 months and are deemed unsuitable for surgery by researchers; 9.Patients with abnormal liver and kidney function (ALT and AST values exceeding 1.5 times the upper limit of normal, or creatinine exceeding normal); 10.Poorly controlled diabetes (fasting blood glucose >= 8 mmol/L), poorly controlled hypertension (systolic blood pressure >= 160 mmHg and/or diastolic blood pressure >= 100 mmHg); 11.Pregnant and intending pregnant women of childbearing age and lactating women; 12.Patients who smoke heavily (>= 10 cigarettes/day); 13.Patients with severe mental illness, alcohol or drug abuse; 14.The patient has participated in or is currently participating in clinical trials of other drugs or devices within the past 3 months; 15.Other patients deemed unsuitable for inclusion by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the changes in bone mass in the bone defect filling area after mandibular cyst removal at 3 and 6 months post surgery compared to 1 day post surgery using CBCT imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing status; | — |
Countries
China
Contacts
Public ContactGuo Jun
Sichuan Provincial People's Hospital
Outcome results
None listed