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Exploring the optimal concentration of lidocaine test dose for labor analgesia

Exploring the optimal concentration of lidocaine test dose for labor analgesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103461
Enrollment
Unknown
Registered
2025-05-29
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delivery?Labor analgesia

Interventions

Group 1:3 ml of 1.5% lidocaine
Group 2:5 ml of 1% lidocaine
Group 3:10 ml of 0.5% lidocaine

Sponsors

The 2nd Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Singleton primipara; 2. Aged 20-40 years; 3. Pre-assessed as eligible for vaginal delivery; 4. Height between 155-170 cm, BMI between 18.5-35 kg/m²; 5. Cervical dilation between 2-6 cm; 6. No significant history of cardiopulmonary disease; 7. No history of surgical trauma; 8. American Society of Anesthesiologists (ASA) Grades I-III; 9. Patients are willing to participate and be able to understand and sign an informed consent form;

Exclusion criteria

Exclusion criteria: 1. Contraindications for spinal anesthesia, such as coagulopathy or ongoing anticoagulant therapy, infection at the puncture site, bacteremia, epidural abscess, increased intracranial pressure, severe hypovolemia; 2. Physical or mental disabilities, such as scoliosis and depression, alcohol or drug abuse; 3. Major organ diseases, such as hyperthyroidism, cardiopulmonary diseases, diabetes treated with insulin, and neuromuscular diseases; 4. Numerical Pain Rating Scale (NPRS) < 5; 5. Refusal to participate in the study;

Design outcomes

Primary

MeasureTime frame
The incidence of motor block;

Secondary

MeasureTime frame
Maternal Pulse oximetry (SPO2);Sensory block level;Maternal blood pressure;First stage of labor;frequency and intensity of uterine contractions;Pain scores;Time of analgesia onset;Maternal heart rate;Second stage of labor;neonatal Apgar score;fetal heart rate;Patient satisfaction score;Incidence of complications related to labor analges;

Countries

China

Contacts

Public ContactChen Bing

The 2nd Affiliated Hospital of Chongqing Medical University

chenbing2050@163.com+86 23 62887913

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026