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Experimental study on TWSG1 regulating BMP7/SMAD pathway to promote VSMC phenotype transition and participate in CKD related AS progression

Experimental study on TWSG1 regulating BMP7/SMAD pathway to promote VSMC phenotype transition and participate in CKD related AS progression

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103458
Enrollment
Unknown
Registered
2025-05-29
Start date
2024-09-06
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Coronary heart disease patients without kidney disease:none
Coronary heart disease patients with chronic kidney disease:none

Sponsors

The Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Screening of coronary heart disease patients over 18 years old diagnosed by angiography

Exclusion criteria

Exclusion criteria: cardiogenic shock Severe liver dysfunction Previous coronary artery treatments such as PCI, CABG, PTCA, thrombolysis, etc

Design outcomes

Primary

MeasureTime frame
TWSG1;—

Countries

China

Contacts

Public ContactHou Jingbo

The Second Affiliated Hospital of Harbin Medical University

Jingbohou@163.com+86 133 0360 9625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026