Thyroid cancer
Conditions
Interventions
Treatment group:In the treatment group, prior to incision closure, Sapylin 10 KE was mixed with 20 mL of normal saline and injected into the thyroid surgical field via the drainage tube. The drainage
Control group:In the treatment group, prior to incision closure, Sapylin 10 KE was mixed with 20 mL of normal saline and injected into the thyroid surgical field via the drainage tube. The drainage tu
Sponsors
The Second Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The age of the patient is between 20 and 70 years old; 2. The tumor has no infiltration of perithyroid organs and no metastasis of distant organs; 3. Before surgery, laryngoscopy showed normal vocal cord function; 4. No significant abnormal laboratory test results before surgery; 5. Postoperative pathology is papillary thyroid carcinoma.TC.
Exclusion criteria
Exclusion criteria: 1. Patients with positive penicillin skin test; 2. Have coagulation disorders or anticoagulation therapy; 3. Uncontrolled diabetes mellitus or hypertension; 4. History of previous thyroid surgery; 5. Second operation due to postoperative complications such as bleeding and infection; 6. Obesity (body mass index > 35 kg/m^2); 7. Failure to sign informed consent; 8. Open surgery or intraoperative transfer to open surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drain amount (postoperative day 1);Drain amount (postoperative day 2);Drain amount (postoperative day 3);Drain amount (total);Day of drain remova; | — |
Secondary
| Measure | Time frame |
|---|---|
| White blood cell(WBC);Neutrophilic granulocyte (NEUT%);C-reactive protein(CRP);Seroma;Neck stiffness;Xerostomia;Dysphagia;Hoarseness ;Dysphonia;Globus sensation;Scar discomfort;Cold intolerance;Heat intolerance;Hot flushes;Myalgia;Feet or hands numbness;Muscle spasm;Sluggish movement;Weight gain;Dry eyes;Pruritus;Palpitations;Headache;Fatigue;Difficulty thinking clearly;Difficulty concentrating;Irritability;Anxiety;Sexual disinterest; | — |
Countries
China
Contacts
Public ContactJun Huang
The Second Affiliated Hospital of Guangxi Medical University
Outcome results
None listed