The patient underwent mechanical ventilation due to respiratory failure.
Conditions
Interventions
aspiration group:NA
Non-aspiration group:NA
Sponsors
The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age > 18 years; 2. Patients admitted to the general ICU of the First Affiliated Hospital of Zhejiang University School of Medicine due to acute respiratory failure; 3. Expected duration of mechanical ventilation > 48 hours; 4. Obtain approval from the attending physician; 5. Informed consent was obtained from the patient or his/her immediate family member.
Exclusion criteria
Exclusion criteria: 1. Hospitalized or have a history of hospitalization within one month prior to recruitment; 2. History of cardiovascular or cerebrovascular events within the past 12 months; 3. pregnant; 4. Patients with advanced cancer or advanced disease; 5. Active neurological or muscular disease; 6. Patients with cerebral coma, brain death, or status epilepticus; 7. Serious mental health problems (such as depression with psychotic features, bipolar disorder, or schizophrenia); 8. Patients receiving neuromuscular blocking agents (NMBAs).
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Natural airway inner diameter; | — |
Primary
| Measure | Time frame |
|---|---|
| Respiratory effort(PMI,POCC);a-Amylase;central drive p0.1; | — |
Countries
China
Contacts
Public ContactHe Guojun
The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed