Obesity
Conditions
Interventions
Control group:None
Sponsors
Fuzhou First General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Complete medical records. (2) No history of cardiovascular or inflammatory diseases, and exclusion of secondary obesity. (3) Age 18 to 80 . (4) No severe kidney or liver diseases. (5) Not using medications that may affect P2RX2 expression, such as metformin, GLP-1 receptor agonists (GLP-1RA), or sodium-glucose cotransporter 2 inhibitors (SGLT2i). (6) BMI greater than 30 Kg/m^2. (7) No history of pregnancy or tumor.
Exclusion criteria
Exclusion criteria: (1) Incomplete medical records. (2) History of cardiovascular or inflammatory diseases, or secondary obesity. (3) Age 80 years. (4) Severe kidney or liver diseases. (5) Use of medications that may affect P2RX2 expression, such as metformin, GLP-1 receptor agonists (GLP-1RA), or sodium-glucose cotransporter 2 inhibitors (SGLT2i). (6) BMI less than 30 Kg/m^2. (7) Pregnancy or a definitive history of cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood lipids;Body mass index;High-throughput sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Blood lipids; | — |
Countries
China
Contacts
Public ContactLiu Fengmin, Xie Diya
Fuzhou First General Hospital
Outcome results
None listed