Single subcortical stroke, watershed stroke, and arterial to arterial thrombotic stroke within 48 hours of onset
Conditions
Interventions
Progressive infarction group:None
Non-progressive infarction group:None
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 40 years old; 2.Admission within 48 hours of onset and completion of first MRI examination (the time of symptom onset is defined as the "last time it appears normal"); 3.Cerebral infarction that meets the following definitions (single subcortical infarction, watershed infarction, arterial to arterial thrombotic infarction, watershed infarction combined with arterial to arterial thrombotic infarction); 4.Signed informed consent form;
Exclusion criteria
Exclusion criteria: 1.Diagnosis of bleeding or other pathological brain disorders based on baseline MRI, such as tumors, abscesses, or other common non ischemic brain disease cases such as multiple sclerosis; 2.Progressive infarction has been made before admission; 3.Pre admission mRS score of 3-5 points; 4.There are contraindications to the use of antiplatelet drugs and statins; 5.There is a risk of using antiplatelet drugs and statins; 6.Received emergency thrombectomy, arterial thrombolysis, and thrombolysis treatment; 7.Suspected cerebral infarction caused by other mechanisms (dissection, moyamoya disease, tumor); 8.Suspected presence of cardioembolic factors such as atrial fibrillation, known artificial heart valves, suspected endocarditis, etc; 9.Cerebral infarction caused by angioplasty/vascular surgery; 10.Severe heart failure (NYHA grade III and IV); 11.Women of childbearing age who have tested negative for pregnancy but refuse to take effective contraceptive measures, as well as pregnant or lactating women; 12.Mental disorders, cognitive or emotional disorders, inability to understand and/or comply with research procedures and/or follow-up; 13.Receiving experimental drug or instrument testing; 14.Due to any reason, the patient cannot be followed up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progressive cerebral infarction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progressive cerebral infarction;Progressive cerebral infarction;Changes in neurological disability;quality of life; | — |
Countries
China
Contacts
Public ContactDaojun Hong
The first affiliated hostipal of nanchang university
Outcome results
None listed