Autism Spectrum Disorder,ASD
Conditions
Interventions
ABA treatment control group:applied behavior analysis,ABA
rTMS treatment group:rTMS
rTMS placebo control group:Repetitive transcranial magnetic pseudo-stimulation
Blank control group:None
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 4 to 12 years old; 2.Meet the diagnostic criteria for autism spectrum disorder in DSM-5; 3.Be able to complete the treatment as required within the research period; 4.The patient or the parents agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Suffer from a serious physical illness; 2.Suffer from mental disorders such as attention deficit hyperactivity disorder, bipolar disorder, schizophrenia, and mental retardation; 3.Suffer from neurological diseases such as epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Childhood Autism Rating Scale (CARS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalogram detection;Non-targeted blood metabolomics;Plasma arginine vasopressin;Plasma oxytocin;Red blood cell trace elements, macronutrients, rare earth elements (more than 40 kinds);Plasma or saliva oxidative stress series, including nitrate, nitrite, plasma iron reduction capacity (FRAP), malondialdehyde (MDA), free radical scavenging capacity (ABTS), reduced glutathione (GSH),; | — |
Countries
China
Contacts
Public ContactYueqin Huang
Peking University Sixth Hospital
Outcome results
None listed