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The neural mechanisms of aggressive behavior in schizophrenia: An event-related potential study based on the competitive reaction time task

The neural mechanisms of aggressive behavior in schizophrenia: An event-related potential study based on the competitive reaction time task

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103393
Enrollment
Unknown
Registered
2025-05-28
Start date
2024-04-17
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Schizophrenia group:None
Control group:None

Sponsors

Wuxi Mental Health Center of Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Schizophrenia Group Inclusion Criteria: 1. Meet the diagnostic criteria for schizophrenia in the American Psychiatric Association's Statistical Diagnostic Manual of Mental Disorders, Fifth Edition (DSM-5); 2. Age 18-65 years old; 3. Positive and Negative Syndrome Scale (PANSS) > 70 points; 4. Modified Overt Aggression Scale (MOAS) score > 5 points; 5. Education level is not lower than junior high school (usually no less than 9 years of education); 6. Guardians with informed consent and collaborators. Healthy control group (30 cases) Inclusion Criteria: 1. Match the ethnicity, age, gender and education level of the patient group; 2. No previous occurrence of assault causing personal injury, Buss and Perry Assault Questionnaire Chinese version < 55 points; 3. No history of mental illness and no family history of schizophrenia.

Exclusion criteria

Exclusion criteria: Schizophrenia Group Exclusion Criteria: 1. Meet the criteria for any other psychiatric illness in the DSM-5; 2. Those who have a history of electroconvulsive treatment in the past six months; 3. Use of drugs that affect cognitive function, such as barbiturates, benzodiazepines, etc., two weeks before enrollment; 4. Current or previous neurological diseases or any other serious physical diseases that affect cognitive function; Exclusion Criteria for Healthy Control Group: 1. History of cerebral organic disorder, visual and hearing impairment; 2. Have a history of drug abuse and alcoholism;

Design outcomes

Primary

MeasureTime frame
Event-related potential;

Countries

China

Contacts

Public ContactZhenhe Zhou

Wuxi Mental Health Center of Jiangsu Province

zlzl55395673@163.com+86 138 6260 3356

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026