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Observation of the Clinical Efficacy of Ciprofol in the Induction of General Anesthesia in Hypertensive Patients

Observation of the Clinical Efficacy of Ciprofol in the Induction of General Anesthesia in Hypertensive Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103391
Enrollment
Unknown
Registered
2025-05-28
Start date
2025-06-05
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Group P:Anesthesia induction and maintenance were performed using propofol.
Group C:Anesthesia induction and maintenance were performed using propofol.

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-65 years, ASA physical status I-II 2.Patients with a documented history of hypertension 3.Blood pressure measurements upon entering the operating room showing systolic blood pressure (SBP) of 140-179 mmHg and/or diastolic blood pressure (DBP) of 90-109 mmHg 4.Body mass index (BMI) ranging from 18 to 28 kg/m^2

Exclusion criteria

Exclusion criteria: 1.Blood pressure >180/110 mmHg upon entering the operating room; body mass index (BMI) >= 28 kg/m^2 2.Patients with hepatic or renal insufficiency; anticipated difficult airway 3.Known or suspected allergy to study-related medications 4.Presence of psychiatric disorders or cognitive impairment 5.Administration of sedatives/anesthetics within 24 hours prior to anesthesia induction

Design outcomes

Primary

MeasureTime frame
Hemodynamics change;

Secondary

MeasureTime frame
Incidence of hypotension and bradycardia;Adverse reactions during operation;Postoperative adverse reaction;Quality of recovery;Time of unconsciousness;Recovery time;

Countries

China

Contacts

Public ContactFanceng Ji

Weifang People's Hospital, Shandong Province

jifanceng@163.com+86 135 6369 8838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026