A registry and efficacy comparison study in acute ischemic stroke of 6-24 h with perfusion mismatch

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500103389

Enrollment

Unknown

Registered

2025-05-28

Start date

2025-06-03

Completion date

Unknown

Last updated

2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Ischemic Stroke

Interventions

reperfusion group:reperfusion therapy, IVT/EVT

control group:standard stroke care

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. age>= 18 years old; 2. Patients diagnosed with acute ischemic stroke; 3. Symptom onset within 6-24h; 4. Patients completed perfusion imaging(CTP or MRP), and mismatch ratio>1.2; peaumbra volume>10ml; core <70ml; 5. Participant consent (waived for retrospective cohort); 6. Stroke center with more than 50 reperfusion cases/year.

Exclusion criteria

Exclusion criteria: 1. Patients for whom reperfusion therapy is contraindicated; 2. Patients with large infarct core(ASPECTS70ml); 3. Patients with severe comorbidities; 4. Patients who can't complete follow-up.

Design outcomes

Primary

Measure	Time frame
modified Rankin Scale;	—

Secondary

Measure	Time frame
Early Neurological Improvement;Symptomatic intracranial hemorrhage;Mortality;	—

Countries

China

Contacts

Public ContactSong Xiaowei

Beijing Tsinghua Changgung Hospital

songxiaowei0914@126.com+86 188 1036 3866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026