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Comparison of the effect of remazolam toluene sulfonate and propofol in the operation of elderly urinary calculi

Comparison of the effect of remazolam toluene sulfonate and propofol in the operation of elderly urinary calculi

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103383
Enrollment
Unknown
Registered
2025-05-28
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary calculus

Interventions

Remazolam group:Induction of anesthesia: Intravenous injection of Remazolam benzoate (0.2×Kg)ml, i.e. 0.2 mg/kg, intravenous injection of Sufentanil citrate injection 0.3µg/kg and rocuronium bromide 0

Sponsors

Jintang County first People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Age 60 to 90 years old, BMI(18.5-30kg/m^2); 2. Elective urolithiasis surgery, operation duration > 1 hour, anesthesia method: tracheal intubation general anesthesia; 3.clear mind, no mental disorders, intellectual disabilities and other diseases; 4.ASA classification: I-III; Cardiac function: Grades 1-3.

Exclusion criteria

Exclusion criteria: 1. With heart, lung and other vital organ failure; 2. Acute and chronic systemic infection; 3.A long history of antipsychotic drug use; 4. Allergies to drugs used in this study; 5.Patients who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
RASS sedative agitation score;CAM-CR delirium score;

Secondary

MeasureTime frame
meanarterialpressure;heart rate;Pulse Oxygen Saturation;Recovery time;Extubation time;Recovery room residence time;C-reactive protein;

Countries

China

Contacts

Public Contactlideyuan

Jintang County first People's Hospital

1839077375@qq.com+86 159 0819 8639

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026