Aizheimer's disease
Conditions
Interventions
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Adults between the ages of 55 and 90 and speak Mandarin fluently. While people with family history of autosomal dominant or other familial AD are not limited by age; 2.The score on the Geriatric Depression Scale (GDS) is less than 6 points; 3.Visual and auditory acuity is sufficient for neuropsychological testing (Including normal corrected vision and hearing); 4.Female participants are not pregnant, lactating, or of childbearing potential (that is, women must be two years postmenopausal or surgically sterile); 5.A modified version of the Hachinski Ischemic scores less than or equal to 4; 6.Have completed primary school (6 years of education) or have good work experience (sufficient to rule out mental retardation).
Exclusion criteria
Exclusion criteria: Individuals with an infection, infarction, or other focal lesions or multiple lacunes or lacunes in critical memory structures and who do not meet the MRI scanning requirements are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Longitudinal changes of cognitive function _ ADAS-Cog;Longitudinal changes of cognitive function _ MMSE, the Chinese version;Longitudinal changes of cognitive function _ MoCA-Basic;Longitudinal functional and behavioral function _ CDR;Longitudinal functional and behavioral function _ NPI;Longitudinal functional and behavioral function _ GDS;Longitudinal functional and behavioral function _ FAQ;Longitudinal functional and behavioral function _ ADL;Longitudinal functional and behavioral function _ PSQI;Longitudinal functional and behavioral function _ RBDSQ; | — |
Countries
China
Contacts
Public ContactTao Liu
Hainan General Hospital
Outcome results
None listed