Gastrointestinal Tumors
Conditions
Interventions
Bupivacaine liposome (observation) group:Transversus abdominis plane block using bupivacaine liposomes
Ropivacaine (control) group:Transversus abdominis plane block using ropivacaine
Sponsors
Capital Medical University,Beijing Friendship Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients planning to undergo laparoscopic assisted radical resection for colorectal cancer; 2. Age range from 30 to 75 years old; 3.BMI 18~30 kg/m^2; 4. ASA classification 1-2 levels; 5. Understand the informed consent form and agree to sign it before this study.
Exclusion criteria
Exclusion criteria: 1. There are contraindications for regional nerve block (puncture site infection, coagulation dysfunction, local anesthetic allergy); 2. Combining chronic pulmonary and bronchial diseases, old cerebral infarction, transient ischemic attack, sleep apnea syndrome, liver and kidney dysfunction, or mental illness; 3. Long term use of opioid drugs; 4. Refusing to sign informed consent forms, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 72 hours postoperative opioid dosage (oral morphine milligram equivalent); | — |
Secondary
| Measure | Time frame |
|---|---|
| Perceived range of block plane, surgical time, anesthesia time;Intraoperative dosages of remifentanil and propofol;Time of first postoperative analgesia and number of remedies;PACU(1h),6h,12h,24h,48h72hNRS;Incidence of postoperative nausea and vomiting;hospital stay;patient satisfaction;First landing time; | — |
Countries
China
Contacts
Public ContactHu Zhenfa
Capital Medical University,Beijing Friendship Hospital
Outcome results
None listed