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A randomized and controlled clinical study of ultrasound-guided cervical vagus nerve block to reduce postoperative nausea and vomiting in people at high risk of PONV

A randomized and controlled clinical study of ultrasound-guided cervical vagus nerve block to reduce postoperative nausea and vomiting in people at high risk of PONV

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103339
Enrollment
Unknown
Registered
2025-05-28
Start date
2024-07-11
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting (PONV)

Interventions

Experimental group:Left cervical vagus block under ultrasound guidance
Control group:Use a sterile 22G ( No. 7 needle)to perform skin puncture + compression at the same site

Sponsors

Army Medical Center of the Chinese Peoples Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Gynecologic endoscopic surgery with the surgical grade of 3-4;Age 18-70 years old,American society of Anesthesiologists level I-III under general anesthesia; 2.Apfel simplifies postoperative nausea and vomiting risk scoring >= three points; 3.Agree to participate in this study and sign the informed consent;

Exclusion criteria

Exclusion criteria: 1.Impaired vocal cords (e.g. hoarseness, electronic laryngoscopy showing fixed vocal cords or dislocation of arytenoid cartilage); 2.History of left neck surgery (e.g. thyroidectomy); 3.Puncture site infection; 4.Severe coagulation dysfunction; 5.Allergic to ropivacaine; 6.Have serious heart and lung disease, irregular heart rate; 7.Liver and kidney failure; 8.Study participants who are participating in other clinical trials; 9.People who have difficulty communicating; 10.Other reasons deemed unsuitable for clinical trial candidates;

Design outcomes

Primary

MeasureTime frame
Incidence of Grade III-IV nausea and vomiting in participants of post operative nausea and vomiting high-risk study 24 hours after operation;

Secondary

MeasureTime frame
Incidence of Grade III-IV nausea and vomiting in high-risk study participants at different postoperative time points (T1: 2h, T2: 6h, T3: 12h, T4: 24h).;

Countries

China

Contacts

Public ContactQingxiang Mao

Army Medical Center of the Chinese Peoples Liberation Army

maomaosmmu@126.com+86 13594054231

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026