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A study on the application of bupivacaine combined with dexamethasone in ultrasound-guided pudendal nerve block via the gluteal approach in gynecological pelvic floor reconstruction surgery

A study on the application of bupivacaine combined with dexamethasone in ultrasound-guided pudendal nerve block via the gluteal approach in gynecological pelvic floor reconstruction surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103321
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain

Interventions

Control group:General anesthesia
Experimental group:Ultrasound-guided transgluteal nerve block (PNB) combined with general anesthesia

Sponsors

The 900th Hospital of the Joint Logistics Support Force of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with pelvic organ prolapse scheduled for pelvic floor reconstruction under general anesthesia; 2. American Society of Anesthesiologists (ASA) physical status I-III; 3. Age 45-85 years old; 4. BMI 18-30 kg/m^2; 5. Voluntary participation in the study.

Exclusion criteria

Exclusion criteria: 1. History of chronic pain; 2. Allergy to local anesthetics; 3. Infection at the injection site; 4. Coagulation dysfunction; 5. Those with poor control of blood pressure or blood glucose and severe complications (preoperative systolic blood pressure > 160 mmHg, diastolic blood pressure > 100 mmHg, fasting blood glucose > 6.5 mmol/L); 6. Patients with poor compliance and communication disorders cannot understand the Visual Analogue Scale (VAS) score or the usage of patient-controlled intravenous analgesia (PCIA).

Design outcomes

Primary

MeasureTime frame
pain;

Secondary

MeasureTime frame
remifentanil dosage;propofol dosage;cardiovascular events;first press time of analgesic pump;PCA effective press times;times of remedial analgesia;first exhaust time;first time out of bed;length of stay;

Countries

China

Contacts

Public ContactChen dongsheng

The 900th Hospital of the Joint Logistics Support Force of the People's Liberation Army of China

cdsheng315@sohu.com+86 137 0505 0101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026