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Clinical pharmacokinetics and individualized medication research of antimicrobial agents in critically Ill patients with severe infections

Clinical pharmacokinetics and individualized medication research of antimicrobial agents in critically Ill patients with severe infections

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103320
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-05-30
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe infection

Interventions

Caspofungin group:None
Omacycline group:None
Imipenem group:None

Sponsors

The Second Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Having full capacity for civil conduct and being aged 18 years or older; (2) Being diagnosed with severe infection; (3) Clinically indicated to require the use of antimicrobial agents such as teicoplanin, tigecycline, caspofungin, omadacycline, meropenem, imipenem, and linezolid; (4) Having relevant blood drug concentration monitoring data; (5) Volunteering to participate in the trial and signing the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Pregnant or lactating women; (2) Those who have not used the antimicrobial agents under study or have not undergone blood drug concentration monitoring after using the antimicrobial agents under study; (3) Patients who have not been diagnosed with severe infection; (4) Other circumstances deemed unsuitable for enrollment by the researchers.

Design outcomes

Primary

MeasureTime frame
Plasma concentration;

Countries

China

Contacts

Public ContactYu Yunli

The Second Affiliated Hospital of Soochow University

haoyyl0902@163.com+86 133 8214 7113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026