Infertility complicated with hyperlipidemia
Conditions
Interventions
?-3 fatty acid intervention group:Provide pre-pregnancy diet and exercise guidance for this group of patients: This includes cooking with less oil, controlling sugar with less salt, appropriately incr
Blank control group:Only pre-pregnancy dietary and exercise guidance was provided, without supplementation of omega-3 fatty acid preparations.
Sponsors
Guangzhou Medical University Affiliated Qingyuan Hospital (Qingyuan People's Hospital)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Infertile patients aged 20-38 years with combined hyperlipidemia and undergoing IVF/ICSI-ET assisted pregnancy; 2) 18 kg/m ² = Body mass index (BMI) 1.1 ng/ml, AFC on both ovaries > 5-7, basal FSH < 10 IU/L; 5) Voluntarily and agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1) Clearly identify diseases that affect the structure and function of the uterus, such as uterine malformations, submucosal fibroids, intramural fibroids that affect the shape of the uterine cavity, and severe adenomyosis of the uterus; History of endometrial tuberculosis, abnormal endometrial hyperplasia lesions, intrauterine adhesions. 2) Stage III-IV endometriosis, preconception diabetes, and untreated thyroid dysfunction. 3) Untreated hydrosalpinx; 4) Chromosomal abnormalities of either spouse; 5) Recurrent miscarriage and repeated implantation failure; 6) Have a habit of smoking and drinking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of mature eggs (MII);Rate of high-quality embryos;Number of retrieved oocytes;Normal fertilization (2PN) rate;The changes in blood lipid levels before pregnancy and between the start date of ovulation induction;Abortion rate;The incidence of moderate to severe OHSS (late-onset); | — |
Countries
China
Contacts
Public ContactCairong Chen
Guangzhou Medical University Affiliated Qingyuan Hospital (Qingyuan People's Hospital)
Outcome results
None listed