Calculi in pancreatic duct and bile duct
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA ? or ?; 2.BMI 18~28kg/m^2; 3.Age 18-65 years old; 4.Patients undergoing ESWL?
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding women and patients (including men) who plan to have a baby within 3 months; 2.There were obvious respiratory and circulatory dysfunction, abnormal blood routine and blood biochemical indexes before operation; 3.Suffering from severe neuropsychiatric diseases; 4.Taking opioids daily for 1 month or intermittently for nearly 3 months; 5.People who are allergic or contraindicated to opioids, propofol, naloxone and other drugs and their drug components; 6.Patients judged to have difficulty managing the respiratory tract: modified Markov score level III and above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Somatokinetic response during surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time from administration to BIS < 65, time of operation, time to recovery, and time after operation when subjects reached the standard for leaving the anesthesia recovery room;Heart rate, blood pressure (systolic/diastolic), respiratory rate, blood oxygen saturation (SPO2), and BIS values after the initiation of administration until the end of the procedure after the subjec;Adverse events that occur during surgery;Postoperative visual analogue scale (VAS) score; | — |
Countries
China
Contacts
Affiliated hangzhou first people's hospital, zhejiang university school of medicine