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Prospective multicenter study on sequential treatment for hepatocellular carcinoma conversion to clinical complete response

Prospective multicenter study on sequential treatment for hepatocellular carcinoma conversion to clinical complete response

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103307
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Group 1 (Sequential liver transplantation treatment after conversion therapy to complete clinical response):NA
Group 2 (Sequential liver resection treatment after conversion therapy to complete clinical response):NA
Group 3 (Sequential non-surgical treatment after conversion therapy to complete clinical response):NA

Sponsors

Shulan (Hangzhou) Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Age range: 18-85 years old; (2) Diagnosed as HCC based on imaging methods such as computed tomography (CT) and/or magnetic resonance imaging (MRI), characterized by early enhancement and delayed enhancement attenuation; (3) After conversion therapy, the Child Pugh score for liver function was A; (4) There was no extrahepatic metastasis during diagnosis; (5) Successfully achieving complete clinical response after conversion therapy; (6) Complete clinical case information and data; (7) Long term follow-up after surgery.

Exclusion criteria

Exclusion criteria: (1) Recurrent HCC; (2) Accompanied by a history of other malignant tumors; (3) Patients who have not received conversion therapy; (4) CT images with poor quality or incomplete images; (5) Clinical and follow-up data are incomplete.

Design outcomes

Primary

MeasureTime frame
Overall survival, OS;

Secondary

MeasureTime frame
Disease free survival, DFS;Serum parameter;

Countries

China

Contacts

Public ContactZhe Yang

Shulan (Hangzhou) hospital

yangzhe__0201730@163.com+86 158 5822 3762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026