mycoplasma pneumoniae pneumonia
Conditions
Interventions
Macrolide group:Erythromycin
Tetracycline group:Doxycycline
Quinolone group:Levofloxacin/moxifloxacin
Sponsors
Kunming Children's Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Definitive diagnosis of drug-resistant severe Mycoplasma pneumoniae pneumonia 2. Duration: within 2 weeks 3. Age: 1-18 years
Exclusion criteria
Exclusion criteria: 1. The patient has taken tetracycline/quinolone drugs; 2. Suffering from tuberculosis, bronchial asthma, allergic rhinitis and other respiratory diseases; 3. Respiratory system dysplasia and malformation; 4. Previous immunological diseases and history of recent or long-term use of glucocorticoids; 5. Severe cases require admission to ICU for mechanical ventilation; 6. Congenital or acquired immunodeficiency disease; 7. The patient or guardian refuses to participate; 8. Other pathogenic infections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of various clinical symptoms;Single symptom (including temperature, cough, chest pain, dyspnea, etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in inflammatory markers (C-reactive protein, calcitoninogen, blood sedimentation, etc.);radiographic changes;Complications (pulmonary necrosis, embolism, coagulation disorders, central involvement, etc.); | — |
Countries
China
Contacts
Public ContactMing Li
Kunming Children's Hospital
Outcome results
None listed