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To compare and observe the multi-center clinical study of polydocaol injection and different sclerosing agents in the treatment of internal hemorrhoids under the foam state

To compare and observe the multi-center clinical study of polydocaol injection and different sclerosing agents in the treatment of internal hemorrhoids under the foam state

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103297
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-05-30
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Internal hemorrhoids

Interventions

Treatment group:Internal hemorrhoids were treated with 3% polydocarol injection foam hardener
Control group:Other sclerosing agents treat internal hemorrhoids(For example, laurosol)

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-75 years old, male or female; 2. Patients who meet the indications for microscopic treatment of internal hemorrhoids and need elective or emergency treatment: patients with stage I, II, and III hemorrhoids (especially those with bleeding and prolapse) and some internal hemorrhoids combined with uncomplicated mixed syndromes; 3. The patient can follow the follow-up plan; Able to objectively describe symptoms and actively cooperate with the completion of the scale; 4. Sign the informed consent form; 5. Those who have an expected survival time of at least one year; 6. Colonoscopy excludes other intestinal diseases.

Exclusion criteria

Exclusion criteria: 1. Patients with rectal and anal diseases with serious complications (such as incarceration, ulceration, infection, etc.), severe external hemorrhoids, anal fissures; 2. Patients with severe bleeding tendency (relative) and severe heart, lung, liver, brain, and renal failure are not suitable for endoscopy and rectal and anal function examination; 3. Patients who have previously performed rectal and anal surgery and minimally invasive treatment; 4. There are other intestinal diseases, such as ulcerative colitis, Crohn's disease and anal lesions 5. Dentate line area with unexplained ulcer; 6. Pregnant and lactating women; 7. Unable to cooperate with the examination and follow-up for reasons such as lack of cognitive ability; 8. Combined with other serious systemic diseases such as advanced tumors; 9. People with an expected survival time of less than one year.

Design outcomes

Primary

MeasureTime frame
Comparison of the effects before and after endoscopic treatment for patients;Effective rate;Rebleeding rate;

Secondary

MeasureTime frame
Recurrence rate;Complication rate;

Countries

China

Contacts

Public ContactDi Zhang

Sichuan Provincial People's Hospital

Wendy602@sina.com+86 177 0813 0331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026