Chest pain
Conditions
Interventions
Sponsors
People‘s Hospital of Xinjiang Uygur Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years; 2. Disease group: Present to the emergency department for acute chest pain, and the time from chest pain to visit is not more than 2 weeks; Patients with AAD, AMI, or APE diagnosed by electrocardiogram, imaging (CTA/MRI/PCTA), and cardiac enzyme profiles or markers; 3. Healthy control group: no history of acute chest pain, no severe liver and kidney insufficiency, malignant tumors and other diseases. 4. Patient's willingness: The patient or his/her legal representative is willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous clear diagnosis of aortic dissection or chronic aortic dissection, acute cardiac death, pulmonary embolism and other diseases; 2. AAD, AMI and APE have been excluded or other causes of acute chest pain have been clearly diagnosed (such as acute pericarditis, pneumothorax, intercostal neuralgia, etc.); 3. Combined with other serious diseases that may affect the diagnosis, treatment or prognosis evaluation of the diseases under study, such as end-stage organ failure (renal failure, liver failure, respiratory failure, etc.), end-stage malignant tumors, serious infections (such as sepsis), etc.; 4. Patients who have received packed red blood cells, whole blood, or platelet transfusions within 10 days prior to blood sample collection; 5. Patients who have undergone surgical treatment outside the hospital and are admitted to the hospital for examination; 6. Clinical severity or other conditions that do not allow for appropriate enrollment to complete the assessment; 7. Refusal of the patient or his/her legal representative to participate in this study, or inability to sign the informed consent form; or patients who may not be able to complete the 6-month follow-up due to the remote location of the patient, unclear contact information, or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expression level of the ON level in the blood; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events (MACE) incidents; | — |
Countries
China
Contacts
Public ContactYang Yining
People‘s Hospital of Xinjiang Uygur Autonomous Region
Outcome results
None listed