Post-Stroke Motor Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Stroke is diagnosed for the first time through neurological examination, CT or MRI scans. 2. Vital signs are stable, and there is a certain degree of upper limb motor dysfunction. 3. The age ranges from 20 to 80 years old. 4. Cognitive ability is not significantly affected, and the patient is able to cooperate with various examination assessments. The Mini-Mental State Examination (MMSE) score is >=20 points. 5. There are no severe complications (such as pneumonia, heart failure, urinary tract infection or malnutrition). 6. There is no pathological condition that is a contraindication for transcranial magnetic stimulation (TMS) in the medical history (for example, patients with metal in the brain, such as aneurysm clips, patients with a cardiac pacemaker, pregnant women, or those with a history of epileptic seizures). 7. The patient or the guardian agrees to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, lung, liver, kidney diseases or malignant tumors; 2. Those with aphasia, severe cognitive impairment or a history of mental illness; 3. Patients who have had a history of epileptic seizures in the last month or have recently taken anti-epileptic drugs; 4. Those with severe visual or hearing impairments, unable to communicate normally; 5. Individuals with metal implants, pacemakers, skull defects or other conditions that prevent transcranial magnetic stimulation (TMS) from being carried out.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment of Upper Extremity,FAM-UE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor evoked potential;Wolf motor function test;Modified Barthel Index;Pittsburgh sleep quality index;Average completion time for baseline task;Side effect scale;TMS-EEG assessment;MRI assessment; | — |
Countries
China
Contacts
Shanghai Yangzhi Rehabilitation Hospital