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Transcranial Magnetic Stimulation in Conjunction with Specific Motor Task Training for Alleviating Post-Stroke Upper Limb Motor Dysfunction

Transcranial Magnetic Stimulation in Conjunction with Specific Motor Task Training for Alleviating Post-Stroke Upper Limb Motor Dysfunction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103274
Enrollment
Unknown
Registered
2025-05-27
Start date
2024-04-14
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-Stroke Motor Dysfunction

Interventions

Online group:Online rTMS
Offline group:Offline rTMS
Preliminary Experiment (Online Stimulation Group):Online rTMS

Sponsors

Shanghai Yangzhi Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Stroke is diagnosed for the first time through neurological examination, CT or MRI scans. 2. Vital signs are stable, and there is a certain degree of upper limb motor dysfunction. 3. The age ranges from 20 to 80 years old. 4. Cognitive ability is not significantly affected, and the patient is able to cooperate with various examination assessments. The Mini-Mental State Examination (MMSE) score is >=20 points. 5. There are no severe complications (such as pneumonia, heart failure, urinary tract infection or malnutrition). 6. There is no pathological condition that is a contraindication for transcranial magnetic stimulation (TMS) in the medical history (for example, patients with metal in the brain, such as aneurysm clips, patients with a cardiac pacemaker, pregnant women, or those with a history of epileptic seizures). 7. The patient or the guardian agrees to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, lung, liver, kidney diseases or malignant tumors; 2. Those with aphasia, severe cognitive impairment or a history of mental illness; 3. Patients who have had a history of epileptic seizures in the last month or have recently taken anti-epileptic drugs; 4. Those with severe visual or hearing impairments, unable to communicate normally; 5. Individuals with metal implants, pacemakers, skull defects or other conditions that prevent transcranial magnetic stimulation (TMS) from being carried out.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment of Upper Extremity,FAM-UE;

Secondary

MeasureTime frame
Motor evoked potential;Wolf motor function test;Modified Barthel Index;Pittsburgh sleep quality index;Average completion time for baseline task;Side effect scale;TMS-EEG assessment;MRI assessment;

Countries

China

Contacts

Public ContactDanmei Lan

Shanghai Yangzhi Rehabilitation Hospital

landanmei2013@163.com+86 18521308136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026