Sepsis and Sepsis Shock
Conditions
Interventions
Low CD4 T lymphocyte ATP release level group:None
High CD4 T lymphocyte ATP release level group:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years; 2. Patients who were admitted to Nanfang Hospital of Southern Medical University from May 2022 to March 2024, admitted to ICU and diagnosed with sepsis; 3. Sepsis meets the Sepsis3.0 definition and diagnostic criteria;
Exclusion criteria
Exclusion criteria: 1.Presence of autoimmune disease or history of immunosuppressive therapy within 8 weeks prior to admission. 2.Pregnant or breastfeeding women; 3.End-stage malignancy; 4.Sepsis patients deemed unsuitable for inclusion in this study based on the investigator’s judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In-hospital mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative incidence of hospital-acquired infections;Cumulative incidence of multiple organ dysfunction syndrome (MODS);28-day mortality;Cumulative incidence of patients diagnosed with sepsis at admission developing into septic shock;ICU length of stay; | — |
Countries
China
Contacts
Public ContactLiu Yanan
Southern Medical University Southern Hospital
Outcome results
None listed