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Clinical efficacy of peripheral magnetic stimulation in the treatment of facial paralysis

Clinical efficacy of peripheral magnetic stimulation in the treatment of facial paralysis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103245
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All the patients with Bell facial palsy were selected as outpatients in the rehabilitation department of our hospital.Subjects in sequelae stage of peripheral facial palsy should exclude peripheral facial nerve paralysis caused by facial neuroma, intracranial trauma, brain stem hemorrhage or infarction, and suppurative inflammation. The course of the disease was longer than 3 months.

Interventions

Magnetic stimulation group:On the basis of facial function training, magnetic stimulation of peripheral facial nerve was added
Control group:Facial function training

Sponsors

Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Patients with facial neuritis with no significant response after more than 3 months of conservative treatment (acupuncture and oral drugs). 2.Patient age:18 years old <=Patient age<=90 years old; 3.In nerve electrical excitation test, bilateral difference greater than 3.5mA indicated irreversible degeneration of facial nerve caused by axon, intimal nerve interruption or fascicular nerve interruption. 4.The House-Brackmann facial nerve rating system was evaluated as grade III-VI (moderate to severe facial paralysis), and facial muscle linkage symptoms were present.

Exclusion criteria

Exclusion criteria: 1.Neuroelectric excitation test, no response to 10mA stimulation indicates complete nerve dysfunction due to nerve root injury. 2.Neuroelectric excitation test with less than 3.5mA suggests only temporary nerve dysfunction, and facial nerve function can be restored. 3.Facial nerve paralysis caused by trigeminal nerve tumor, intracranial and extracranial injury, cerebellar hemorrhage or infarction. 4.MRI, electrophysiology, and TMS contraindications, such as metal implants in the cranial or cranial cavity. 5.Cognitive impairment or any significant underlying disease. 6.Known to be taking drugs that interfere with cortical excitability, such as GABA, benzodiazepines, and baclofen, and stopped at least 2 weeks prior to the study.

Design outcomes

Primary

MeasureTime frame
Fisch face features score indicators;

Secondary

MeasureTime frame
Degree of facial nerve degeneration (ENoG);Image objective evaluation of mouth-eye linkage movement;Amplitude of facial nerve electroencephalogram;

Countries

China

Contacts

Public ContactMao Yeran

Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine

1429700284@qq.com+86 18621065251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026