All the patients with Bell facial palsy were selected as outpatients in the rehabilitation department of our hospital.Subjects in sequelae stage of peripheral facial palsy should exclude peripheral facial nerve paralysis caused by facial neuroma, intracranial trauma, brain stem hemorrhage or infarction, and suppurative inflammation. The course of the disease was longer than 3 months.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with facial neuritis with no significant response after more than 3 months of conservative treatment (acupuncture and oral drugs). 2.Patient age:18 years old <=Patient age<=90 years old; 3.In nerve electrical excitation test, bilateral difference greater than 3.5mA indicated irreversible degeneration of facial nerve caused by axon, intimal nerve interruption or fascicular nerve interruption. 4.The House-Brackmann facial nerve rating system was evaluated as grade III-VI (moderate to severe facial paralysis), and facial muscle linkage symptoms were present.
Exclusion criteria
Exclusion criteria: 1.Neuroelectric excitation test, no response to 10mA stimulation indicates complete nerve dysfunction due to nerve root injury. 2.Neuroelectric excitation test with less than 3.5mA suggests only temporary nerve dysfunction, and facial nerve function can be restored. 3.Facial nerve paralysis caused by trigeminal nerve tumor, intracranial and extracranial injury, cerebellar hemorrhage or infarction. 4.MRI, electrophysiology, and TMS contraindications, such as metal implants in the cranial or cranial cavity. 5.Cognitive impairment or any significant underlying disease. 6.Known to be taking drugs that interfere with cortical excitability, such as GABA, benzodiazepines, and baclofen, and stopped at least 2 weeks prior to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fisch face features score indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of facial nerve degeneration (ENoG);Image objective evaluation of mouth-eye linkage movement;Amplitude of facial nerve electroencephalogram; | — |
Countries
China
Contacts
Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine