lung cancer
Conditions
Interventions
Control group: Treatment plans developed by single-disciplinary physicians. :NA
Test group: Personalized regimens formulated through Multidisciplinary Team (MDT) discussions.:NA
Sponsors
West China Hospital, Sichuan university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Participants voluntarily join the study, have signed the informed consent form, and agree to cooperate with follow-up; (2) Diagnosed with unresectable locally advanced (stage IIIB or IIIC) or metastatic (stage IV) lung cancer (based on AJCC 9th edition) confirmed by histology/cytology at the Lung Cancer Center of West China Hospital, Sichuan University; (3) Age >=18 years, regardless of gender; (4) Planned to receive antitumor therapy and able to provide informed consent; (5) The MDT group must have undergone at least one Multidisciplinary Team (MDT) discussion (intra-hospital, inter-hospital, or outpatient); (6) Expected survival period >=3 months; (7) No use of relevant antidepressant medications within the past 3 months; (8) Good compliance and cooperation with follow-up.
Exclusion criteria
Exclusion criteria: (1) Presence of comorbid malignancies (other coexisting cancers); (2) History of psychoactive substance abuse with inability to abstain, or diagnosed psychiatric disorders; (3) Substance-induced depressive disorders (related to addictive or non-addictive psychoactive substances); (4) Psychogenic depression (depression caused by psychological factors); (5) Impaired communication or comprehension abilities, making psychological assessments infeasible; (6) Other conditions deemed by investigators to likely lead to premature study termination, such as: - Severe comorbidities (including psychiatric illnesses) requiring concurrent treatment; - Critically abnormal laboratory values; - Social/family factors hindering long-term follow-up; (7) Other scenarios judged by investigators as unsuitable for inclusion (e.g., patients receiving palliative care only); (8) Elevated suicide risk, necessitating transfer to a closed psychiatric care facility.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety and Depression Scores;Suicide Risk Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Quality Index;Treatment-related Adverse Events;Median PFS; | — |
Countries
China
Contacts
Public ContactLingling Zhu
west china hospital, sichuan university
Outcome results
None listed