Stroke
Conditions
Interventions
Gold Standard:1. The gold standard for diagnosing cerebral hemorrhage: the first head CT scan after arrival at the hospital.
2. The gold standard for GFAP detection: ELISA method.
Index test:Detection of GFAP Concentration in Whole Blood from Human Peripheral Blood
Sponsors
Shanghai East Hospital (Tongji University Affiliated East Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Suspected stroke at emergency department arrival (FAST score >= 2 points, must include limb weakness); 3. Time of stroke symptom onset/last known normal within 3 hours.
Exclusion criteria
Exclusion criteria: 1. Coma - no response to tactile or verbal stimuli; 2. Severe comorbidities (such as tumors, severe COPD, severe heart failure, requiring assistance with daily living [unable to walk independently]); 3. History of epilepsy or onset with seizure; 4. Recent history of head trauma (< 7 days); 5.Blood glucose < 2.8 mmol/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;cut-off value;The accuracy of whole blood testing instruments; | — |
Countries
China
Contacts
Public ContactLi Gang
Shanghai East Hospital, Tongji University School of Medicine
Outcome results
None listed