Post-stroke cognitive impairment
Conditions
Interventions
Pre-iTBS :iTBS stimulates the left dorsolateral prefrontal lobe.
Sham stimulus control group:Sham stimulation was performed in the control group.
Sponsors
Zhongshan City People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Clear diagnosis of ischemic stroke, and all of them have been confirmed by brain MRI scan as a single lesion; 2. First stroke, and in the subacute stage (within 6 weeks of onset); 3. Right hand; 4. Age 18-80 years old; 5. Stable condition with no progressive neurological symptoms; 6. Informed and willing to participate in this clinical study; 7. Able to cooperate in the completion of all neuropsychological tests and EEG recordings.
Exclusion criteria
Exclusion criteria: 1. Multi-site or large-area ischemic stroke confirmed by cranial MR; 2. There are contraindications to TMS treatment, such as metal implants, pacemakers or skull defects in the body; 3. Have a history or risk of seizures or have taken anti-epileptic drugs; 4. Previous neuroorganic lesions of the brain, such as brain tumor or traumatic brain injury, and history of brain surgery; 5. The patient has serious diseases of important organs such as heart, liver, kidney or other serious physical diseases; 6. The patient has a history of organic psychosis or affective psychosis or related diseases, such as schizophrenia or depression; 7. Those who cannot complete neuropsychological tests and EEG recordings; 8. Long-term history of alcoholism, severe alcohol abuse and drug abuse; 9. Pregnant women; 10. Refusal to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute power; | — |
Secondary
| Measure | Time frame |
|---|---|
| Relative Power;Inter-band Power Ratio;Brain Symmetry Power Ratio; | — |
Countries
China
Contacts
Public ContactXu Ruikai
Zhongshan City People’s Hospital
Outcome results
None listed