spinal cord injury
Conditions
Interventions
Group A:Group A patients received iTBS stimulation therapy on the basis of routine rehabilitation treatment.
Group B:Group B patients were given isokinetic muscle strength training on the basis of routine rehabilitation treatment.
Group C:Group C received isokinetic muscle strength training combined with iTBS stimulation therapy on the basis of routine rehabilitation treatment.
Sponsors
China Rehabilitation Research Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Meets the evaluation criteria of the International Classification of Spinal Cord Injury Neurology (revised in 2021) and is confirmed by medical history and imaging examinations to have spinal cord injury; 2) Incomplete spinal cord injury (AISAC or D) involving the cervical spine (C4, C5, C6, C7); 3) Improved Ashworth Scale (MAS)= 21 on the Mini Mental State Examination (MMSE).
Exclusion criteria
Exclusion criteria: 1) Individuals with fractures, severely restricted joint mobility, deformities, or amputations; 2) SCI caused by multiple sclerosis, spinal cord hemangioma, or spinal cord tumor; 3) Contraindications for TMS, such as patients implanted with pacemakers, deep brain stimulators, Baclofen pumps, or any ferromagnetic metal implants near the target stimulation area, or those who lack tolerance to TMS and have skull defects; Accompanied by neurological disorders, including any history of epilepsy and polyneuropathy; 4) Individuals with active infectious diseases such as pulmonary tuberculosis, severe cardiovascular and cerebrovascular diseases, and liver and kidney dysfunction; 5) Patients with severe cognitive impairment; 6) Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spinal cord independence assessment scale (SCIM-III);Latency and amplitude of motor evoked potential (MEP); | — |
Secondary
| Measure | Time frame |
|---|---|
| Joint range of motion;Muscle Strength;Upper Limb Function Questionnaire (CUE-Q);tonicity of muscles;Functional Near Infrared Spectroscopy (fNIRS); | — |
Countries
China
Contacts
Public ContactJunming Liu
China Rehabilitation Research Center,Beijing Boai Hospital
Outcome results
None listed