Lung mass
Conditions
Interventions
Intubation group:After general anesthesia induction, a double-lumen bronchial tube was inserted orally, and one-lung ventilation was performed during surgery.
spontaneous breathing anesthesia group:After induction of general anesthesia, a laryngeal mask airway (LMA) was inserted orally for ventilation. During the thoracoscopic surgery, intercostal nerve blo
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing thoracoscopic wedge resection of the lung; 2.Age: 18–65 years; 3.Complete preoperative examinations; 4.Written informed consent obtained from the patient or their legal guardian.
Exclusion criteria
Exclusion criteria: Age under 18 years or over 65 years. Pregnant or breastfeeding women. Presence of thrombocytopenic disorders. Uncontrolled infection or sepsis. Severe diseases of other major organs (heart, lungs, kidneys, etc.). Preoperative anemia: hemoglobin 37.5°C on the day before surgery. Patients who have undergone tracheostomy or other traumatic procedures, or those on long-term mechanical ventilation, which are prone to secondary infections. Presence of myasthenia gravis. Intraoperative resuscitation events, such as cardiopulmonary resuscitation. Central nervous system disorders. Presence of hyperthyroidism or hypothyroidism. Presence of other malignancies. Allergy to anesthetic agents. Family history of malignant hyperthermia. Alcohol dependence or long-term use of sedative-hypnotic drugs. Difficult airway: Mallampati airway classification grade III or IV, temporomandibular joint ankylosis, limited mouth opening (< 2 cm), facial deformity, or ankylosing spondylitis. History of radiotherapy or chemotherapy. Participation in other clinical trials. Patients deemed by the investigators to be unsuitable for the clinical trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic parameter changes(invisive blood pressure, heart rate and cvp);Respiratory Mechanics(Partial Pressure of Carbon Dioxide,Tidal Volume Airway Pressure);Blood gas analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Imaging Studies; | — |
Countries
China
Contacts
Public ContactLan Lan
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed