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The Effect of Conscious Sedation on Adverse Events During Painless Gastrointestinal Endoscopy in Elderly Patients: A Randomized Controlled Trial

The Effect of Conscious Sedation on Adverse Events During Painless Gastrointestinal Endoscopy in Elderly Patients: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103214
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless gastroscopy and colonoscopy for elderly patients

Interventions

Conventional anesthesia group:Conventional-dose propofol-fentanyl intravenous anesthesia
Conscious sedation group:Anesthesia with low-dose remifentanil combined with minimal propofol

Sponsors

Shanghai East Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 65-80 years old 2. Proposed painless gastrointestinal endoscopy or surgery 3. ASA grading I-IV

Exclusion criteria

Exclusion criteria: 1. Complex endoscopic diagnosis and treatment techniques are required 2. Hypertension is not satisfactorily controlled 3. Myocardial infarction or cerebral infarction within the past 3 months 4. Recent use of opioids and benzodiazepines 5. Have a history of alcohol or drug abuse 6. Severe systemic disease 7. Those who are allergic to the drugs used in this study 8. Combined neurological diseases 9. Has participated in other clinical trials

Design outcomes

Primary

MeasureTime frame
Incidence of oxygen desaturation;

Secondary

MeasureTime frame
Incidence of hypotension;Incidence of nausea and vomiting;Incidence of nausea and vomiting;

Countries

China

Contacts

Public ContactLiu Feng

Shanghai East Hospital

liufeng0295@163.com+86 188 5426 0295

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026