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Clinical study of mannitol in preventing postoperative nausea and vomiting after posterior scleral reinforcement

Clinical study of mannitol in preventing postoperative nausea and vomiting after posterior scleral reinforcement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103212
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-06-09
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Control group:Tropisetron and Dexamethasone
Test group:Tropisetron and Dexamethasone in combination with Mannitol

Sponsors

Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective unilateral posterior scleral reinforcement under general anesthesia ; 2. ASA I-II ; 3. Aged 18-60 years.

Exclusion criteria

Exclusion criteria: 1. History of motion sickness; 2. Personal or family history of PONV (Postoperative Nausea and Vomiting); 3. BMI = 25 ; 4. Presence of severe heart, lung, liver, or kidney diseases; 5. Presence of severe hypertension or diabetes; 6. Patients with a confirmed history of allergy to such medications prior to surgery.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Score (VAS);Simplified PONV Intensity Scale (Four-Grade Scoring);PONV Severity Score;—

Countries

China

Contacts

Public ContactYe Wenlian

Eye Hospital of Wenzhou Medical University

ywl@eye.ac.cn+86 139 0664 7839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026