Endometriosis
Conditions
Interventions
Experimental group:Dydrogesterone
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) Female, aged>=18 years and<=45 years, and signed an informed consent form; 2) Patients diagnosed with endometriosis after surgery; 3) Patients who are willing to receive long-term management of levonorgestrel after surgery; 4) Within the first 3 months of participating in this study, no other hormone therapy for endometriosis was received. 5) Patients with good compliance and cooperation in follow-up;
Exclusion criteria
Exclusion criteria: 1) Symptoms such as pelvic pain and vaginal bleeding caused by unknown reasons or reasons other than endometriosis; 2) Known or suspected malignant tumors; 3) Postoperative treatment with other hormone or GnRH-a drugs for endometriosis; 4) Personnel who are currently using other drugs that interact with the investigational drug and cannot stop taking the drug will be informed in detail of their medication situation, and the researchers will make a judgment for them; 5) Patients with severe heart, liver, and kidney diseases, as well as those with adrenal cortex dysfunction; 6) Patients with active digestive ulcers or drug allergies or allergic constitutions; 7) Participated in other clinical trials within 3 months; 8) Those with fertility needs; 9) And factors that other personnel believe you are not suitable to participate in the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence rate of endometriosis cysts after 12 months of postoperative medication; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life;Menstrual changes;The recurrence rate of pain (pelvic pain, dysmenorrhea, painful intercourse);The recurrence rate of endometriosis cysts after 24 months of postoperative medication;Liver function, coagulation function, blood lipids; | — |
Countries
China
Contacts
Public ContactXinmei Zhang
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed