Patients with lung nodules or lung cancer
Conditions
Interventions
Room temperature group (liposomal bupivacaine at 11-20°C):None
Low temperature group (liposomal bupivacaine at a temperature of 4-10°C):None
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing thoracoscopic surgery under elective general anesthesia. 2.It is rated I-III by the American College of Anesthesiologists. 3.Communicate well, participate voluntarily, sign informed consent forms and have the ability to comply with follow-up plans as well as other research requirements.
Exclusion criteria
Exclusion criteria: 1.Anesthesia puncture site infection; 2.Coagulation disorders; 3.Experimental drug allergy; 4.Upper extremity nerve injury or compression, history of mental illness. 5.Participated in other clinical trials within the past 3 months. 6.There is severe organ failure, such as heart failure, acute myocardial infarction, respiratory failure, kidney failure, and liver failure. 7.History of chronic pain or preoperative lung puncture localization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the pain score curve for patients in active state 0-72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;The incidence of postoperative adverse events;The dosage of opioid drugs used during and after the surgery;The average arterial pressure and heart rate during skin incision;Postoperative recovery quality score and nausea vomiting score;Postoperative Prince-Henry score;Preoperative and postoperative systemic immune-inflammatory index;Postoperative NRS static score;Postoperative hospital stay days;The onset time of sensory nerve block; | — |
Countries
China
Contacts
Public ContactDanyang Wang
Shanghai Pulmonary Hospital
Outcome results
None listed