Cancer-related anorexia
Conditions
Interventions
Acupuncture group:Acupuncture (Heji acupoint+Sixian acupoint)+placebo
drug group (positive control):Mifepristone acetic acid dispersible tablet (manufacturer: Qingdao Guohai Biopharmaceutical Co., Ltd.), 1 tablet each time, once a day, take continuously for 14 days.
control group (negative control):The patient takes a placebo once a day at 8am for a total of 2 weeks.
Sponsors
Beijing Hospital of Integrated Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patient was diagnosed as malignant tumor by histological cytology; 2. Patients who meet the above diagnostic criteria and have no obvious eating disorders; 3. Age >=18 years old and =3 months; 5. Patients who did not participate in other trials or subjects and did not receive radiotherapy, chemotherapy or surgery during the observation period; 6. KPS score >=30 points; 7. Those who agree to accept the treatment plan of this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who are unable to eat orally, such as dysphagia, parenteral nutrition, and indentation of gastric tubes; 2. Acute or chronic digestive diseases; 3. Complicated with serious heart, brain, lung, liver, kidney, endocrine, blood, immune diseases, end-stage diseases; 4. Patients with long-term coma and lethargy; 5. Alzheimer's disease; 6. Communication difficulties caused by hearing and speech disorders; 7. Use of appetite promoting drugs or treatment in the recent 1 month; 8. Participation in clinical trials of tumor treatment within the recent 1 month may interfere with the conclusions of this study; 9. Non-cancerous anorexia, such as anorexia nervosa related to psychological factors; 10. Patients who are dizzy with needles.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of appetite score before and after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in body mass index before and after treatment;Changes in nutritional biochemical indices before and after treatment;KPS scores before and after treatment;TCM symptom scores before and after treatment;Quality of survival scores for cancer patients before and after treatment; | — |
Countries
China
Contacts
Public ContactJuhua Yuan
Beijing Hospital of Integrated Chinese and Western Medicine
Outcome results
None listed