Postoperative Delirium
Conditions
Interventions
Test group:Small doses of dexmedetomidine were continuously pumped at a rate of 0.4 µg/kg/h from the beginning of the surgery to the end of the surgery in the experimental group group, and patient-con
Control group:The control group group did not undergo any intraoperative drug pumping as a control. Patient controlled analgesic pump (PCIA) was used in all patients postoperatively Control group grou
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
70 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) 70 17; (5) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Known intolerance or hypersensitivity to dexmedetomidine; (2) Previously diagnosed or suspected significant neurocognitive dysfunction in patients with a score =17 on the Brief Mental State Examination (MMSE); (3) Severe audiovisual impairment; (4) Traumatic brain injury; intracranial hemorrhage <1 year prior to inclusion date; (5) Preoperative Pittsburgh Sleepiness Scale assessment with a score <15; (5) Hepatic and renal insufficiency; (6) Planned deep postoperative sedation (RASS value of -4-5); (7) Those who were allergic to postoperative analgesic pump medications. (8) Refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative sleep;hemodynamics;Pain scores;Anxiety severity; | — |
Countries
China
Contacts
Public ContactWang Gongming
Shandong Provincial Hospital
Outcome results
None listed