Acute ischemic stroke
Conditions
Interventions
Control group:none
DNT 30-minute group:Stroke green channel process and related measures targeting 30 minutes of DNT
Sponsors
Chengdu Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Symptoms of neurological deficit due to ischemic stroke; 3. 0-4.5 h of symptom onset; 2. Age >= 18 years; 3. Signed informed consent by patient or family member;
Exclusion criteria
Exclusion criteria: 1. Intracranial hemorrhage (including parenchymal hemorrhage, intraventricular hemorrhage, subarachnoid hemorrhage, subdural/extracranial hematoma, etc.); 2. History of previous intracranial hemorrhage; 3. History of severe head trauma or stroke within the last 3 months; 4. Intracranial tumor, giant intracranial aneurysm; 5. Recent (3 months) intracranial or intraspinal surgery; 6. Major surgery in the last 2 weeks; 7. Gastrointestinal or urinary bleeding in the last 3 weeks; 8. Active visceral hemorrhage; 9. Aortic arch entrapment; 10. Arterial puncture at a site not easily compressible for hemostasis within the last 1 week; 11. Elevated blood pressure: systolic blood pressure >= 180 mmHg or diastolic blood pressure >= 100 mmHg; 12. Acute hemorrhagic tendency, including platelet count 1.7 or PT >15 s; 15. Use of thrombin inhibitors or factor Xa inhibitors within 48 h, or abnormalities in various laboratory tests (e.g., APTT, INR, platelet count, ECT, TT, or factor Xa activity assay); 16. Blood glucose 22.22 mmol/L; 17. Large infarcts (infarct size >1/3 of the middle cerebral artery blood-supplying area) on CT or MRI of the head;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of DNT <=30 minutes pre- and post-intervention;Clinical outcomes before and after the intervention;Median DNT before and after intervention; | — |
Countries
China
Contacts
Public ContactWang Jian
Chengdu Second People's Hospital
Outcome results
None listed