Bicuspid aortic valve associated aortopathy
Conditions
Interventions
Control group (patients undergoing only aortic valve replacement):Only aortic valve replacement, without concurrent ascending/aortic root replacement.
treatment group (patients requiring aortic valve replacement who also undergo concurrent ascending/aortic root replacement):Patients requiring aortic valve replacement who also undergo concurrent asc
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The subject (or legal guardian) understands the trial requirements and treatment procedures, signs a written informed consent form, and purchases medical insurance; 2. Age >=18 years; 3.Chest aortic CTA shows the ascending/aortic root diameter between 40-45mm; 4. Preoperative TTE and intraoperative exploration confirm the patient has BAV; 5. Patients requiring other cardiac surgeries, including AVR.
Exclusion criteria
Exclusion criteria: 1. Patients with acute type A aortic dissection; 2. History of previous aortic root surgery; 3. Combined with other complex congenital diseases (such as Turner syndrome, Marfan syndrome, etc.); 4. Severe comorbidities (end-stage organ failure, malignant tumors, etc.) resulting in a life expectancy of < 1 year; 5. Refusal of surgery by the patient and/or family.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reintervention rate;All-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Aortic complications; | — |
Countries
China
Contacts
Public ContactZhenghua Xiao
West China Hospital of Sichuan University
Outcome results
None listed