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Study on the Association of bFGF and TGF-ß1 Gene Polymorphisms and Expressions with In-Stent Restenosis of the Vertebral Artery in the Han Chinese Populatio

Study on the Association of bFGF and TGF-ß1 Gene Polymorphisms and Expressions with In-Stent Restenosis of the Vertebral Artery in the Han Chinese Populatio

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103100
Enrollment
Unknown
Registered
2025-05-23
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In-stent restenosis after vertebral artery stenting

Interventions

Group of in-stent restenosis :NA
Group of non-in-stent restenosis :NA

Sponsors

Maoming People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old. 2. Symptomatic atherosclerotic stenosis of the vertebral artery. And underwent bare stent angioplasty. 3. There were no severe perioperative complications. 4. Written informed consent was obtained from patients or their legal representatives. 5. The subjects and their legal representatives are willing to follow the follow-up requirements of the protocol.

Exclusion criteria

Exclusion criteria: 1. Patients with intracranial hemorrhage and intracranial tumors. 2. Complicated with serious cardiovascular, blood, liver and kidney diseases. 3. Severe coagulopathy is absolutely contraindicated to antiplatelet therapy. 4. Contraindications to cerebral angiography. 5. Life expectancy less than 6 months. 6. Refusal to sign the relevant research consent form.

Design outcomes

Primary

MeasureTime frame
in-stent restenosis within the vertebral artery stent ;

Secondary

MeasureTime frame
bFGF (rs308395) gene polymorphism;TGF-ß1 (rs1800470) gene polymorphism;Serum level of bFGF;Serum levels of TGF-ß1;

Countries

China

Contacts

Public ContactGeng Liao

Maoming People's Hospital

Legendv@126.com+86 186 6681 8299

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026