Intracranial bleeding or bleeding from other organs
Conditions
Interventions
prevention group:Vitamin K1 tablets taken orally
control group:No special treatment or oral placebo
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1.Pregnant women with preterm birth <32 weeks gestational age;
Exclusion criteria
Exclusion criteria: 1.Pregnant women who are allergic to the drugs used; 2.Pregnant women with liver and gallbladder disease and broad bean disease; 3.Pregnant women are using drugs that affect vitamin K metabolism such as anticonvulsants, anticoagulants, antituberculosis drugs, etc; 4.Neonates with severe birth trauma or severe asphyxia;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intracranial hemorrhage; | — |
Secondary
| Measure | Time frame |
|---|---|
| vitamin deficiency induced protein PIVKA-?;vitamin K1 concentration; | — |
Countries
China
Contacts
Public ContactMinli Zhu
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed