Hilar cholangiocarcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >18 years old; 2. The preoperative imaging diagnosis is pCCA, and the conditions to complete the radical resection of the tumor, and there is no substantial tumor invasion in the left and right trunks of the portal vein; 3. Intraoperative exploration confirmed that the tumor is mainly located in the central area of the hepatic portal, and has not widely invaded the hepatic parenchyma on one side, and there is no tumor invasion in the trunk, bifurcation and secondary branch of the extrahepatic portal vein; 4. Postoperative pathology confirmed pCCA;
Exclusion criteria
Exclusion criteria: 1. Researchers believe that severe cardiopulmonary insufficiency, renal insufficiency, etc. may affect the evaluation factors; 2. Intraoperative exploration found that the tumour had bilateral intrahepatic metastasis, distant organ metastasis or intra-abdominal implant metastasis, and there were no conditions for tumour root treatment; 3. Bilateral portal vein involvement, portal vein bifurcation or trunk involvement is extensive and cannot be reconstructed by vascular resection; 4. Suffering from any other serious diseases that researchers believe may affect the evaluation factors, including but not limited to any uncontrolled neurological and mental diseases, immunomodulatory diseases, metabolic diseases and infectious diseases; 5. Patients with other malignant tumors before or at the same time, except in the following cases:In situ cancer of cervical cancer or breast cancer, after curative treatment, showed no signs of recurrence at least 3 years before the study;The primary malignant tumor has been completely removed and completely relieved for >5 years; 6. Antitumor treatment (including chemotherapy, small molecule targeting, clinical drug trials) has been carried out before joining the group; 7. Research participants have participated in dialysis in the past; 8. Patients with incomplete follow-up information and missed visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative liver failure;Overall Survival, OS;RFS rate;incidence of complications; | — |
Countries
China
Contacts
The First Affiliated Hospital of Army Medical University