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Clinical application study of albumin-bilirubin grading in predicting the perioperative risk of radical resection of hepatic portal bile duct cancer

Clinical application study of albumin-bilirubin grading in predicting the perioperative risk of radical resection of hepatic portal bile duct cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500103074
Enrollment
Unknown
Registered
2025-05-23
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hilar cholangiocarcinoma

Interventions

ALBI Level 1:NA
ALBI Level 2:NA
ALBI Level 3:NA

Sponsors

The First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >18 years old; 2. The preoperative imaging diagnosis is pCCA, and the conditions to complete the radical resection of the tumor, and there is no substantial tumor invasion in the left and right trunks of the portal vein; 3. Intraoperative exploration confirmed that the tumor is mainly located in the central area of the hepatic portal, and has not widely invaded the hepatic parenchyma on one side, and there is no tumor invasion in the trunk, bifurcation and secondary branch of the extrahepatic portal vein; 4. Postoperative pathology confirmed pCCA;

Exclusion criteria

Exclusion criteria: 1. Researchers believe that severe cardiopulmonary insufficiency, renal insufficiency, etc. may affect the evaluation factors; 2. Intraoperative exploration found that the tumour had bilateral intrahepatic metastasis, distant organ metastasis or intra-abdominal implant metastasis, and there were no conditions for tumour root treatment; 3. Bilateral portal vein involvement, portal vein bifurcation or trunk involvement is extensive and cannot be reconstructed by vascular resection; 4. Suffering from any other serious diseases that researchers believe may affect the evaluation factors, including but not limited to any uncontrolled neurological and mental diseases, immunomodulatory diseases, metabolic diseases and infectious diseases; 5. Patients with other malignant tumors before or at the same time, except in the following cases:In situ cancer of cervical cancer or breast cancer, after curative treatment, showed no signs of recurrence at least 3 years before the study;The primary malignant tumor has been completely removed and completely relieved for >5 years; 6. Antitumor treatment (including chemotherapy, small molecule targeting, clinical drug trials) has been carried out before joining the group; 7. Research participants have participated in dialysis in the past; 8. Patients with incomplete follow-up information and missed visits.

Design outcomes

Primary

MeasureTime frame
Mortality rate;

Secondary

MeasureTime frame
The incidence of postoperative liver failure;Overall Survival, OS;RFS rate;incidence of complications;

Countries

China

Contacts

Public ContactZhiyu Chen

The First Affiliated Hospital of Army Medical University

chenzhiyu_umn@163.com+86 23 65460505

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026