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An fNIRS-based study of brain network mechanisms of impaired executive performance and working memory in nurses after occupational sleep deprivation and the role of rTMS intervention

An fNIRS-based study of brain network mechanisms of impaired executive performance and working memory in nurses after occupational sleep deprivation and the role of rTMS intervention

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500103070
Enrollment
Unknown
Registered
2025-05-23
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Pre-night shift rTMS:Transcranial magnetic stimulation before night shift
After night shift rTMS:Transcranial magnetic stimulation after night shift
Sham rTMS:Sham rTMS immediately after the night shift

Sponsors

The First Affiliated Hospital of Nanhua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for sleep deprived nurses: 1. participating in night shift for >3 months, 4-8 night shifts/month, >=8 hours of a single night shift, and no sleep time during night shift; 2. aged 18-50 years; 3. right-handed; Inclusion criteria for the control group: 1.not involved in night shifts for >=3 months, and night sleep time >=5h; 2. age between 18-50 years;3. right-handed.

Exclusion criteria

Exclusion criteria: 1. Contraindications to rTMS treatment include patients with epilepsy, pregnant or lactating women, or implanted metal or electric devices (such as deep brain stimulators, ventriculoperitoneal shunts, aneurysm clips, pacemakers, cochlear implants, surgical nails on the scalp); 2. There have been major stressful events recently; 3. Have a sleep disorder (PSQI sleep disorder part score > 10 points); 4. Use of caffeine, alcohol, or psychostimulant drugs within 24 hours prior to assessment; 5. History of smoking; 6. Color blindness; 7. Participation in concurrent pharmacological or non-pharmacological treatment studies.

Design outcomes

Primary

MeasureTime frame
HbO2;HbR;Working memory;

Secondary

MeasureTime frame
Executive function;

Countries

China

Contacts

Public ContactFU Jia

The First Affiliated Hospital of Nanhua University

ffjj0528@163.com+86 139 2406 2648

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026